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Targeting EBV Episome for Anti-Cancer Therapy: Emerging Strategies and Challenges

15 Jan 2025

Abstract excerpt

As a ubiquitous human pathogen, the Epstein-Barr virus (EBV) has established lifelong persistent infection in about 95% of the adult population. The EBV infection is associated with approximately 200,000 human cancer cases and 140,000 deaths per year. The presence of EBV in tumor cells provides a unique advantage in targeting the viral genome (also known as episome), to develop anti-cancer therapeutics. In this...

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PMID: 39861899
DOI: 10.3390/v17010110

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