Article
Combination of Biological Aging and Genetic Susceptibility Helps Identifying At-Risk Population of Venous Thromboembolism: A Prospective Cohort Study of 394 041 Participants.
American journal of hematology - 1 Apr 2025
Hu Zhensheng, Xu Jiatang, Shen Runnan, Lin Liling, Su Yangfan, Xie Chaoyu, You Guochang, Zhou Yi, Huang Kai
Abstract excerpt
Phenotypic age acceleration (PhenoAgeAccel) is a novel clinical aging indicator. This study was carried out to investigate the relationship between PhenoAgeAccel and the incidence of VTE, as well as to integrate PhenoAgeAccel with genetic susceptibility to improve risk stratification of VTE. The study included 394 041 individuals from the UK Biobank. Phenotypic age was calculated based on actual age and clinical...
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