Article
Live Attenuated Bacterial Vectors as Vehicles for DNA Vaccine Delivery: A Mini Review
1 Jan 2024
Abstract excerpt
DNA vaccines are third-generation vaccines composed of plasmids that encode vaccine antigens. Their advantages include fast development, safety, stability, and cost effectiveness, which make them an attractive vaccine platform for genetic and infectious diseases. However, the low transfection efficiency of DNA vaccines results in poor performance in both larger animals and humans, thereby limiting their clinical...
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