Article
Prevalence, misclassification, and clinical consequences of the heteroresistant phenotype in Escherichia coli bloodstream infections in patients in Uppsala, Sweden: a retrospective cohort study.
The Lancet. Microbe - 1 Apr 2025
Heyman Gabriel, Jonsson Sofia, Fatsis-Kavalopoulos Nikos, Hjort Karin, Nicoloff Hervé, Furebring Mia, Andersson Dan I
Abstract excerpt
BACKGROUND: Antibiotic heteroresistance is a common bacterial phenotype characterised by the presence of small resistant subpopulations within a susceptible population. During antibiotic exposure, these resistant subpopulations can be enriched and potentially lead to treatment failure. In this study, we examined the prevalence, misclassification, and clinical effect of heteroresistance in Escherichia coli...
Read the complete abstract on PubMedTopics
- Humans
- Escherichia coli Infections
- Sweden
- Escherichia coli
- Retrospective Studies