CohortDiagnostics: Phenotype evaluation across a network of observational data sources using population-level characterization

Abstract excerpt

OBJECTIVE: This paper introduces a novel framework for evaluating phenotype algorithms (PAs) using the open-source tool, Cohort Diagnostics. MATERIALS AND METHODS: The method is based on several diagnostic criteria to evaluate a patient cohort returned by a PA. Diagnostics include estimates of incidence rate, index date entry code breakdown, and prevalence of all observed clinical events prior to, on, and after...

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