Article
PheKB: a catalog and workflow for creating electronic phenotype algorithms for transportability.
Journal of the American Medical Informatics Association : JAMIA - 1 Nov 2016
Kirby Jacqueline C, Speltz Peter, Rasmussen Luke V, Basford Melissa, Gottesman Omri, Peissig Peggy L, Pacheco Jennifer A, Tromp Gerard, Pathak Jyotishman, Carrell David S, Ellis Stephen B, Lingren Todd, Thompson Will K, Savova Guergana, Haines Jonathan, Roden Dan M, Harris Paul A, Denny Joshua C
Abstract excerpt
OBJECTIVE: Health care generated data have become an important source for clinical and genomic research. Often, investigators create and iteratively refine phenotype algorithms to achieve high positive predictive values (PPVs) or sensitivity, thereby identifying valid cases and controls. These algorithms achieve the greatest utility when validated and shared by multiple health care systems.Materials and Methods...
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