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Causal Association between Arm Fat, Left Leg Fat, and Trunk Fat Masses and Risk of Polycystic Ovarian Syndrome: A Mendelian Randomization Study.

Combinatorial chemistry & high throughput screening - 1 Jan 2026

Zhang Yuhan, Zhou Wei, Su Qiong, Chen Qi

Abstract excerpt

BACKGROUND: Observational studies have reported that arm fat, left leg fat, and trunk fat masses have different effects on polycystic ovarian syndrome (PCOS). However, the causal relationship between them remains unknown. MATERIALS AND METHODS: A two-sample Mendelian randomization (MR) study was conducted by utilizing pooled data from the largest Genome-Wide Association Study (GWAS). Random effect inverse...

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Adipose Tissue
Arm
Genome-Wide Association Study
Leg
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polycystic Ovary Syndrome

Polymorphism, Single Nucleotide

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Identifiers

PMID: 39806970
DOI: 10.2174/0113862073325251241101054306
PMCID: PMC13312385

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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