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miRNA Expression Profile in Primary Limbal Epithelial Cells of Aniridia Patients

9 Jan 2025

Abstract excerpt

Purpose: This study evaluates the microRNA (miRNA) expression profile in primary limbal epithelial cells (pLECs) of patients with aniridia. Methods: Primary human LECs were sampled and isolated from 10 patients with aniridia and 10 healthy donors. The miRNA profile was analyzed using miRNA microarrays. The biological roles of miRNA-validated target genes were delineated in silico by the enrichment analyses of the...

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PMID: 39786759
DOI: 10.1167/iovs.66.1.20

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