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Article

Genome-wide analysis suggests a differential microRNA signature associated with normal and diabetic human corneal limbus

8 Jun 2017

Abstract excerpt

Small non-coding RNAs, in particular microRNAs (miRNAs), regulate fine-tuning of gene expression and can impact a wide range of biological processes. However, their roles in normal and diseased limbal epithelial stem cells (LESC) remain unknown. Using deep sequencing analysis, we investigated miRNA expression profiles in central and limbal regions of normal and diabetic human corneas. We identified differentially...

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PMID: 28615632
DOI: 10.1038/s41598-017-03449-7

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