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Cross-species recognition of two porcine coronaviruses to their cellular receptor aminopeptidase N of dogs and seven other species

7 Jan 2025

Abstract excerpt

Porcine deltacoronavirus (PDCoV) and transmissible gastroenteritis coronavirus (TGEV), the two causative agents of porcine diarrhea, have been reported to be at risk of cross-species transmission, including to humans. However, the potential host range in which these two CoVs interact remains unclear. We screened 16 animal counterparts for porcine aminopeptidase N (APN), the receptor of PDCoV and TGEV, and found...

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PMID: 39774464
DOI: 10.1371/journal.ppat.1012836

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