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Article

Primary Human Macrophage and Tenocyte Tendon Healing Phenotypes Changed by Exosomes Per Cell Origin.

Tissue engineering. Part A - 1 Aug 2025

von Stade Devin, Meyers Melinda, Johnson James, Schlegel Theodore, Romeo Anthony, Regan Daniel, McGilvray Kirk

Abstract excerpt

The high failure rate of surgical repair for tendinopathies has spurred interest in adjunct therapies, including exosomes (EVs). Mesenchymal stromal cell (MSC)-derived EVs (MSCdEVs) have been of particular interest as they improve several metrics of tendon healing in animal models. However, research has shown that EVs derived from tissue-native cells, such as tenocytes, are functionally distinct and may better...

Read the complete abstract on PubMed

Topics

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Share to Cytokines
Share to Exosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to MMP13 gene

Share to Macrophages

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Share to Tendons

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Source

Identifiers

PMID: 39761039
DOI: 10.1089/ten.tea.2024.0143

Genes

IL6
MMP13
MMP3
MSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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Primary Human Macrophage and Tenocyte Tendon Healing Phenotypes Changed by Exosomes Per Cell Origin.PMID 39761039Read ↗

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