[Association of the 5HTTLPR/rs25531 Genetic Variant with Depression in a Cohort of Primary Care Patients].

doi:10.4067/s0034-98872024000500577

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Article

[Association of the 5HTTLPR/rs25531 Genetic Variant with Depression in a Cohort of Primary Care Patients].

Revista medica de Chile - 1 May 2024

Lagos-Muñoz Paola, Vicente Benjamín, Schmidt Kristin, Guzmán-Castillo Alejandra, Macaya Ximena, Moraga Esteban, Luis-Castillo Juan, Rojas-Ponce Romina

Abstract excerpt

Serotonin plays a central role in mood regulation and the development of depressive disorders. The serotonin transporter, the primary regulator of serotonin levels, presents genetic variants that affect its functionality. AIM: To study whether functional bi-allelic 5-HTTLPR or tri-allelic 5-HTTLPR/rs25531 polymorphisms in the serotonin transporter gene are associated with the diagnosis of depression. METHODS: The...

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PMID: 39760576
DOI: 10.4067/s0034-98872024000500577

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