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Binding ability of Delta and Omicron towards the angiotensin-converting enzyme 2 receptor and antibodies: a computational study.

Journal of biomolecular structure & dynamics - 1 Nov 2025

Nguyen Quoc-Thai, Mai Tan Thanh, Tuong Lam-Truong, Nguyen Thi-Thao-Nhung, Vo Thanh-Phuong, Nguyen Dac-Nhan, Phan-Van Cong-Thanh, Trinh Dieu-Thuong Thi, Tran Van-Thanh, Thai Khac-Minh

Abstract excerpt

The COVID-19 pandemic posed a threat to global society. Delta and Omicron are concerning variants due to the risk of increasing human-to-human transmissibility and immune evasion. This study aims to evaluate the binding ability of these variants toward the angiotensin-converting enzyme 2 receptor and antibodies using a computational approach. The receptor-binding domain (RBD) of the two variants was created by...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39755961
DOI: 10.1080/07391102.2024.2446659

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