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Article

CXCL8 modulates M0 macrophage proliferation and polarization to influence tumor progression in cervical cancer

4 Jan 2025

Abstract excerpt

Cervical cancer (CESC) presents significant clinical challenges due to its complex tumor microenvironment (TME) and varied treatment responses. This study identified undifferentiated M0 macrophages as high-risk immune cells critically involved in CESC progression. Co-culture experiments further demonstrated that M0 macrophages significantly promoted HeLa cell proliferation, migration, and invasion, underscoring...

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Share to Chemokine receptors and signaling
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39755693
DOI: 10.1038/s41598-024-81726-y

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