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Article

Comprehensive Analysis of the Relationships Between Tumor Mutation Burden With Immune Infiltrates in Cervical Cell Carcinoma

6 Oct 2020

Abstract excerpt

We aimed to investigate the prognosis of tumor mutation burden (TMB) in cervical cell carcinoma (CCC) and its potential association with tumor-infiltrating immune cells. The data from TCGA were analyzed, and higher TMB levels conferred high overall survival time, associated with higher T staging (p = 0.006) and older age (p =2.961e-04). Through "CIBERSORT" package and Wilcoxon rank-sum test, the high TMB group...

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PMID: 33134320
DOI: 10.3389/fmolb.2020.582911

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