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Article

The Expression and Regulation of Chemerin in the Epidermis

6 Feb 2015

Abstract excerpt

Chemerin is a protein ligand for the G protein-coupled receptor CMKLR1 and also binds to two atypical heptahelical receptors, CCRL2 and GPR1. Chemerin is a leukocyte attractant, adipokine, and antimicrobial protein. Although chemerin was initially identified as a highly expressed gene in healthy skin keratinocytes that was downregulated during psoriasis, the regulation of chemerin and its receptors in the skin by...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 25659101
DOI: 10.1371/journal.pone.0117830

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