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Article

Joint effects of atrial fibrillation and prothrombotic genotypes on the risk of ischemic stroke.

Journal of thrombosis and haemostasis : JTH - 1 Apr 2025

Hald Erin Mathiesen, Løchen Maja-Lisa, Mathiesen Ellisiv B, Hveem Kristian, Brækkan Sigrid K, Hansen John-Bjarne

Abstract excerpt

BACKGROUND: Atrial fibrillation (AF) is a major risk factor for ischemic stroke. Whether prothrombotic single nucleotide polymorphisms (SNPs) impact stroke risk in AF is not well known. OBJECTIVES: To investigate the joint effects of 5 prothrombotic SNPs and AF on ischemic stroke risk. METHODS: A subcohort (n = 14 583) was randomly sampled from the Tromsø (1994-2012) and the Trøndelag Health (1995-2008) studies....

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Identifiers

PMID: 39746399
DOI: 10.1016/j.jtha.2024.12.022

Genes

ABO
F11

Variants

rs8176719

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