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Article

Assignment of 2 patients with xeroderma pigmentosum to complementation group E.

Mutation research - 1 Jan 2000

Fujiwara Y, Uehara Y, Ichihashi M, Yamamoto Y, Nishioka K

Abstract excerpt

Xeroderma pigmentosum (XP) fibroblast strains derived from XP24KO and XP26KO patients with mild clinical manifestations were similarly twice as sensitive to 254 nm UV killing as normal cells and had a reduced level of 30-55% unscheduled DNA synthesis (UDS) after irradiation with 10 J/m2. Complementation analysis in the hybridized heterodikaryons revealed that XP24KO and XP26KO cells were only unable to complement...

Topics

Cell Survival
Cells, Cultured
DNA Repair
Genetic Complementation Test
Genetic Linkage
Humans
Hybrid Cells
Mutation
Xeroderma Pigmentosum

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 3974603
DOI: 10.1016/0167-8817(85)90040-9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-3974603-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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