Characterization of molecular defects in xeroderma pigmentosum group F in relation to its clinically mild symptoms.

doi:10.1093/hmg/7.6.969

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Article

Characterization of molecular defects in xeroderma pigmentosum group F in relation to its clinically mild symptoms.

Human molecular genetics - 1 Jun 1998

Matsumura Y, Nishigori C, Yagi T, Imamura S, Takebe H

Abstract excerpt

Xeroderma pigmentosum (XP) complementation group F was first reported in Japan and most XP-F patients reported to date are Japanese. The clinical features of XP-F patients are rather mild, including late onset of skin cancer. Recently a cDNA that corrects the repair deficiency of cultured XP-F ce...

Topics

Adult
Cell Line
DNA Mutational Analysis
DNA-Binding Proteins
Female
Humans
Japan
Male
Middle Aged
Mutation
Polymorphism, Single-Stranded Conformational
RNA, Messenger
Xeroderma Pigmentosum

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