Lack of association of the PLD4 SNP rs2841277 with systemic sclerosis in a European American population.

doi:10.1038/s41598-024-82298-7

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Lack of association of the PLD4 SNP rs2841277 with systemic sclerosis in a European American population.

Scientific reports - 28 Dec 2024

Ma Yunqing, Mayes Maureen D, Guo Xinjian, Assassi Shervin, Zhou Xiaodong

Abstract excerpt

This study aimed to examine whether a reported SSc-associated SNP rs2841277 in the PLD4 gene identified in an Asian population was also associated with SSc in European American (EA). The EA cohort consisting of 1005 SSc patients and 961 healthy controls was examined in this study. TaqMan genotyping assays were performed to examine the SNP. Exact P-values were obtained from 2 × 2 tables of allele counts and...

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PMID: 39730870
DOI: 10.1038/s41598-024-82298-7
PMCID: PMC11681260

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