Dextran sodium sulfate-induced colitis alters the proportion and composition of replicating gut bacteria

Abstract excerpt

ABSTRACT The bacteria living in the human gut are essential for host health. Though the composition and metabolism of these bacteria are well described in both healthy hosts and those with intestinal disease, less is known about the metabolic activity of the gut bacteria prior to, and during, disease development—especially regarding gut bacterial replication. Here, we use a recently developed single-cell...

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