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Article

Optimal intervention timing for craniocerebral radiotherapy in EGFR mutant lung adenocarcinoma patients with brain metastases.

BMC cancer - 23 Dec 2024

Deng Guangchuan, Zhang Qunxing, Fan Jing, Zhao Chenran, Jiao Hui, Li Zhenxiang

Abstract excerpt

BACKGROUND: Intracranial radiation in combination with EGFR targeted therapy demonstrated signals of superiority to EGFR targeted therapy alone based on several observational studies. The timing based on specific criteria is not clear, and we evaluated the efficacy of intervention timing of craniocerebral radiotherapy (RT) combined with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) on...

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Identifiers

PMID: 39716108
DOI: 10.1186/s12885-024-13363-7
PMCID: PMC11664826

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