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Mitochondrial quality control: the real dawn of intervertebral disc degeneration?

20 Dec 2024

Abstract excerpt

Intervertebral disc degeneration is the most common disease in chronic musculoskeletal diseases and the main cause of low back pain, which seriously endangers social health level and increases people's economic burden. Disc degeneration is characterized by NP cell apoptosis, extracellular matrix degradation and disc structure changes. It progresses with age and under the influence of mechanical overload,...

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PMID: 39707402
DOI: 10.1186/s12967-024-05943-9

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