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Article

Reinfection and Resistance Associated Substitutions Following a Minimal Monitoring Approach for Hepatitis C Virus Treatment in MINMON Trial.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 18 Jul 2025

Han Win Min, Solomon Sunil Suhas, Smeaton Laura, Avihingsanon Anchalee, Wagner Cardoso Sandra, Li Jiani, Parvangada Aiyappa, Sulkowski Mark, Naggie Susanna, Martin Ross, Mo Hongmei, Maiorova Evguenia, Wyles David

Abstract excerpt

BACKGROUND: Simplified approaches to hepatitis C virus (HCV) treatment delivery are needed to meet elimination goals. However, the impact of low-touch strategies on individuals at higher risk due to treatment failure or reinfection is unknown. We estimated HCV reinfection rates, and the impact of resistance associated substitutions (RASs) on response in the ACTG A5360 (MINMON) trial. METHODS: HCV RNA evaluations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39702964
DOI: 10.1093/cid/ciae627
PMCID: PMC12272843

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