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Article

Distinct impact modes of polygenic disposition to dyslexia in the adult brain.

Science advances - 20 Dec 2024

Soheili-Nezhad Sourena, Schijven Dick, Mars Rogier B, Fisher Simon E, Francks Clyde

Abstract excerpt

Dyslexia is a common and partially heritable condition that affects reading ability. In a study of up to 35,231 adults, we explored the structural brain correlates of genetic disposition to dyslexia. Individual dyslexia-disposing genetic variants showed distinct patterns of association with brain structure. Independent component analysis revealed various brain networks that each had their own genomic profiles...

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Identifiers

PMID: 39693421
DOI: 10.1126/sciadv.adq2754
PMCID: PMC11654687

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