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MicroRNA‐141‐3p targets DAPK1 and inhibits apoptosis in rat ovarian granulosa cells

22 May 2017

Abstract excerpt

The polycystic ovary syndrome (PCOS) is a complex and heterogeneous endocrine disorder. MicroRNAs negatively regulate the expression of target genes at posttranscriptional level by binding to the 3' untranslated region of target genes. Our previous study showed that miR-141-3p was dramatically decreased in the ovaries of rat PCOS models. In this study, we aimed to characterize the target of miR-141-3p in rat...

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PMID: 28543175
DOI: 10.1002/cbf.3248

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