Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Genetic characteristics and diversity of PDC variants of Pseudomonas aeruginosa and its clinical relevance.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Dec 2024

Karthik Maruthan, Kacha Srujal, Rajendran Subbulakshmi, Bakthavatchalam Yamuna Devi, Lal Binesh, Walia Kamini, Veeraraghavan Balaji

Abstract excerpt

Pseudomonas aeruginosa exhibits significant antibiotic resistance facilitated by both intrinsic and acquired mechanisms, prominently through Pseudomonas-derived cephalosporinase (PDC), serine Ambler class C β-lactamases encoded by the AmpC. AmpC, involved in the peptidoglycan recycling pathway, is regulated by genes such as ampD, ampR, and ampG, leading to increased expression and resistance to various...

Topics

Pseudomonas aeruginosa
Humans
Pseudomonas Infections
beta-Lactamases
Bacterial Proteins
Cephalosporinase
Genetic Variation
Anti-Bacterial Agents
Microbial Sensitivity Tests

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

India

beta-Lactam Resistance

Clinical Relevance

Source

Identifiers

PMID: 39653106
DOI: 10.1016/j.meegid.2024.105701

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic characteristics and diversity of PDC variants of Pseudomonas aeruginosa and its clinical relevance.PMID 39653106Read ↗

Dominance of International High-Risk Clones in Carbapenemase-Producing Pseudomonas aeruginosa: Multicentric Molecular Epidemiology Report from IndiaSemantic proximity Read ↗

Investigating the divergence of β-lactamase PDC variants conferring various antibiotic resistance profiles in Pseudomonas aeruginosa, coupled with the molecular profiling of PDC-266Semantic proximity Read ↗

A Panel of Diverse <i>Pseudomonas aeruginosa</i> Clinical Isolates for Research and DevelopmentSemantic proximity Read ↗

Phylogenomic and phenotypic profiling of carbapenem-resistant Pseudomonas aeruginosa clinical isolates reveals lineage-specific resistance mechanisms and adaptive responses.Semantic proximity Read ↗

Keeping up with the pathogens: improved antimicrobial resistance detection and prediction from Pseudomonas aeruginosa genomes.Semantic proximity Read ↗

Genomic and Phenotypic Insights into Carbapenemase-Mediated Resistance and Clonal Diversity of Pseudomonas aeruginosa Clinical Isolates from Southern Brazil.Semantic proximity Read ↗

Pseudomonas aeruginosa: a clinical and genomics updateSemantic proximity Read ↗

Epidemiological insights into global metallo-β-lactamases-producing pseudomonas aeruginosa: A comprehensive analysis based on NCBI databaseSemantic proximity Read ↗

Screening of Antimicrobial Resistance Genes and Epidemiological Features in Hospital and Community-Associated Carbapenem Resistant Pseudomonas aeruginosa InfectionsSemantic proximity Read ↗

Qualitative analysis of genomic mutations and antibiotic susceptibility testing of Pseudomonas aeruginosa isolates from chronic lung infections.Semantic proximity Read ↗

Comparative genome analysis of carbapenemase-producing Pseudomonas aeruginosa: gene diversity, clonal distribution, and genome dynamics.Semantic proximity Read ↗

Keeping up with the pathogens: Improved antimicrobial resistance detection and prediction from<i>Pseudomonas</i>aeruginosa genomesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.