Article
The host genotype actively shapes its microbiome across generations in laboratory mice.
Microbiome - 5 Dec 2024
Benga Laurentiu, Rehm Anna, Gougoula Christina, Westhoff Philipp, Wachtmeister Thorsten, Benten W Peter M, Engelhardt Eva, Weber Andreas P M, Köhrer Karl, Sager Martin, Janssen Stefan
Abstract excerpt
BACKGROUND: The microbiome greatly affects health and wellbeing. Evolutionarily, it is doubtful that a host would rely on chance alone to pass on microbial colonization to its offspring. However, the literature currently offers only limited evidence regarding two alternative hypotheses: active microbial shaping by host genetic factors or transmission of a microbial maternal legacy. RESULTS: To further dissect the...
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