Paternal microbiome perturbations impact offspring fitness

Abstract excerpt

Abstract The gut microbiota operates at the interface of host–environment interactions to influence human homoeostasis and metabolic networks 1–4 . Environmental factors that unbalance gut microbial ecosystems can therefore shape physiological and disease-associated responses across somatic tissues 5–9 . However, the systemic impact of the gut microbiome on the germline—and consequently on the F 1 offspring it...

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