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Article

Endothelial Cell-Derived Extracellular Vesicles Allow to Differentiate Between Various Endotypes of INOCA: A Multicentre, Prospective, Cohort Study.

Journal of cardiovascular translational research - 1 Apr 2025

Gąsecka Aleksandra, Szolc Piotr, van der Pol Edwin, Niewiara Łukasz, Guzik Bartłomiej, Kleczyński Paweł, Tomaniak Mariusz, Figura Emilia, Zaremba Mateusz, Grabowski Marcin, Kochman Janusz, Legutko Jacek, Kołtowski Łukasz

Abstract excerpt

Ischemia and non-obstructive coronary artery disease (INOCA) might be due to coronary microvascular dysfunction (CMD), vasospastic angina (VSA) or both. We compared plasma concentration of various extracellular vesicles (EVs) in patients with different INOCA endotypes. Patients were divided into those with INOCA (CMD, VSA, mixed CMD + VSA) and non-anginal chest pain. Plasma concentrations of EVs were measured...

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Identifiers

PMID: 39638955
DOI: 10.1007/s12265-024-10575-x
PMCID: PMC12043753

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