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Article

The association between osteoprotegerin and arterial stiffness in a 10-year longitudinal study of patients with type 2 diabetes.

Diabetes & vascular disease research - 1 Jan 2000

Low Serena, Pek Sharon, Moh Angela, Liu Jian-Jun, Pandian Bhuvaneswari, Ang Keven, Tang Wern Ee, Lim Ziliang, Subramaniam Tavintharan, Sum Chee Fang, Lim Su Chi

Abstract excerpt

Introduction: Osteoprotegerin (OPG) inhibits vascular calcification which is central to pathogenesis of arterial stiffness. However, it promotes inflammation by upregulating expression of vascular cell adhesion molecule-1(VCAM-1), thereby contributing to arterial stiffness. We investigated longitudinal association between OPG and arterial stiffness in type 2 diabetes (T2D), causality of the association and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39626773
DOI: 10.1177/14791641241304435
PMCID: PMC11615981

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