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Article

Causal Effects of Sleep Quality on Primary Headache and the Mediation via Gut Microbiota: A Mendelian Randomization Study.

Brain and behavior - 1 Nov 2024

Zhao Huanghong, Guan Dongsheng, Ma Zhen, Yang Minghui, Dong Ning, Guo Jian

Abstract excerpt

BACKGROUND: Previous studies have shown that sleep quality plays an essential role in primary headaches to varying degrees. However, it is unclear precisely whether gut microbiota plays a critical role in mediating changes in sleep quality and affecting primary headaches. METHODS: We utilized Mendelian randomization (MR) to examine the causal relationships between sleep quality and primary headaches. The data...

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Identifiers

PMID: 39607077
DOI: 10.1002/brb3.70129
PMCID: PMC11603430

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