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Article

Causal Association Between Gut Microbiota and Sleep Apnoea Identified by Bayesian Weighted Mendelian Randomisation.

Journal of cellular and molecular medicine - 1 Jan 2026

Zhang Chenguang, Wang Yicong, Yue Guanghao, Guo Bin

Abstract excerpt

This study investigated the potential causal relationship between gut microbiota (GM) and sleep apnoea using Mendelian randomisation (MR) analysis. Summary-level genome-wide association (GWAS) data for 473 GM and sleep apnoea were obtained from the IEU Open GWAS database. A two-sample MR framework was applied to assess the potential causal effects of GM on sleep apnoea. The primary analysis was conducted using...

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Identifiers

PMID: 41501330
DOI: 10.1111/jcmm.70976
PMCID: PMC12779518

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