Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Magnesium-related gene ITGAL: a key immunotherapy predictor and prognostic biomarker in pan-cancer

13 Nov 2024

Abstract excerpt

Background Integrin subunit alpha L (ITGAL) is crucial for activating CD8+ T cells through magnesium-mediated immune synapse formation and specific cytotoxicity. ITGAL might exert an important function in the growth and transformation of cancer. Methods Our study comprehensively analyzed ITGAL expression across various cancers, validated by Immunochemistry (IHC) in the laboratory. ITGAL showed prognostic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers in Disease Mechanisms
Share to Cancer Cells and Metastasis
Share to Ferroptosis and cancer prognosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39605903
DOI: 10.3389/fphar.2024.1464830

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Magnesium-related gene ITGAL: a key immunotherapy predictor and prognostic biomarker in pan-cancerPMID 39605903Read ↗

Integrin Alpha L as an Immune-Related Biomarker Correlated with the Prognosis and Effect of Immunotherapy in GliomasSemantic proximity Read ↗

A Pan-Cancer Analysis of the Oncogenic Role of Integrin Beta4 (ITGB4) in Human TumorsSemantic proximity Read ↗

Pan-cancer analysis of the glycoprotein - associated gene B4GALNT4 with prognositc value and immunological role in malignant tumorsSemantic proximity Read ↗

ITGA5 Is a Novel Oncogenic Biomarker and Correlates With Tumor Immune Microenvironment in GliomasSemantic proximity Read ↗

Comprehensive Analysis of the Expression and Prognosis for ITGBs: Identification of ITGB5 as a Biomarker of Poor Prognosis and Correlated with Immune Infiltrates in Gastric CancerSemantic proximity Read ↗

Identification of GGT5 as a Novel Prognostic Biomarker for Gastric Cancer and its Correlation With Immune Cell InfiltrationSemantic proximity Read ↗

ITGAX promotes gastric cancer progression via epithelial-mesenchymal transition pathwaySemantic proximity Read ↗

CGB5 Proves to be a Promising Predictive and Immunotherapeutic Indicator across Pan-CancerSemantic proximity Read ↗

ITGAL infers adverse prognosis and correlates with immunity in acute myeloid leukemiaSemantic proximity Read ↗

Key Cancer Glycosylation-related Genes Analysis: Regulatory, Therapeutic, and Prognostic InsightsSemantic proximity Read ↗

GLT8D2 is a prognostic biomarker and regulator of immune cell infiltration in gastric cancerSemantic proximity Read ↗

Insights Into the Prognostic Value and Immunological Role of NAAA in Pan-Cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.