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Circulating tumor DNA monitoring for early recurrence detection in epithelial ovarian cancer.

Gynecologic oncology - 1 Nov 2022

Hou June Y, Chapman Jocelyn S, Kalashnikova Ekaterina, Pierson William, Smith-McCune Karen, Pineda Geovanni, Vattakalam Reena Marie, Ross Alexandra, Mills Meredith, Suarez Carlos J, Davis Tracy, Edwards Robert, Boisen Michelle, Sawyer Sarah, Wu Hsin-Ta, Dashner Scott, Aushev Vasily N, George Giby V, Malhotra Meenakshi, Zimmermann Bernhard, Sethi Himanshu, ElNaggar Adam C, Aleshin Alexey, Ford James M

Abstract excerpt

OBJECTIVE: Epithelial ovarian cancer (EOC) is the most lethal gynecologic malignancy. We examined the utility of circulating tumor DNA (ctDNA) as a prognostic biomarker for EOC by assessing its relationship with patient outcome and CA-125, pre-surgically and during post-treatment surveillance. METHODS: Plasma samples were collected from patients with stage I-IV EOC. Cohort A included patients with pre-surgical...

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Identifiers

PMID: 36117009
DOI: 10.1016/j.ygyno.2022.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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