Article
High-throughput genotyping of Plasmodium vivax in the Peruvian Amazon via molecular inversion probes.
Nature communications - 25 Nov 2024
Popkin-Hall Zachary R, Niaré Karamoko, Crudale Rebecca, Simkin Alfred, Fola Abebe A, Sanchez Juan F, Pannebaker Danielle L, Giesbrecht David J, Kim Isaac E, Aydemir Özkan, Bailey Jeffrey A, Valdivia Hugo O, Juliano Jonathan J
Abstract excerpt
Plasmodium vivax transmission occurs throughout the tropics and is an emerging threat in areas of Plasmodium falciparum decline, causing relapse infections that complicate treatment and control. Targeted sequencing for P. falciparum has been widely deployed to detect population structure and the geographic spread of antimalarial and diagnostic resistance. However, there are fewer such tools for P. vivax....
Topics
- Plasmodium vivax
- Peru
- Malaria, Vivax
- Humans
- Polymorphism, Single Nucleotide
- Genotyping Techniques
- Genotype
- Antimalarials
- Drug Resistance
- Molecular Probes