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Article

Genetically predicted serum ferritin mediates the association between inflammatory cytokines and non-alcoholic fatty liver disease.

Frontiers in endocrinology - 1 Jan 2024

Liu XiaoQian, Jin JianHong, Wang BaoFa, Ge LinPu

Abstract excerpt

Objective: Investigating the causal relationship between inflammatory cytokines and Non-alcoholic fatty liver disease(NAFLD) and identifying and quantifying the role of serum ferritin as a potential mediator. Methods: Genetic summary statistics were derived from open genome-wide association study (GWAS) databases. We conducted a two-sample Mendelian randomization (MR) analysis to investigate the relationship...

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Identifiers

PMID: 39583964
DOI: 10.3389/fendo.2024.1437999
PMCID: PMC11581845

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