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Article

Genetic variations in Vitamin D Binding Protein (VDBP) impact vitamin D level and asthma susceptibility across the four ethnic populations.

Asian Pacific journal of allergy and immunology - 1 Mar 2026

Hsieh Miao-Hsi, Paramonova Natalia, Gradauskiene Sitkauskiene Brigita, Trapina Ilva, Rumba-Rozenfelde Ingrida, Munkhbayarlakh Sonomjamts, Plavina Samanta, Sjakste Nikolajs, Bastyte Daina, Tamasauskiene Laura, Stakaitiene Ieva, Ugenskiene Rasa, Chen Pei-Chi, Wang Jiu-Yao, Wu Lawrence Shih-Hsin

Abstract excerpt

BACKGROUND: Asthma are associated with the vitamin D axis. Genetic variations of VDBP, notably rs7041 and rs4588, influence circulating vitamin D levels. However, data on their link to asthma are inconsistent, and ethnic differences remain unclear. OBJECTIVE: We explored how genetic variations in VDBP affect vitamin D levels and susceptibility to asthma across diverse ethnic populations. METHODS: In our...

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PMID: 39580629
DOI: 10.12932/AP-240324-1825

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