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Stopping the Intergenerational Risk of Diabetes—From Mechanisms to Interventions: A Report on Research Supported by Pathway to Stop Diabetes

18 Nov 2024

Abstract excerpt

Embedded in the developmental origins of health and disease (DOHaD) hypothesis, maternal hyperglycemia in utero, from preexisting diabetes or gestational diabetes mellitus, predisposes the offspring to excess adiposity and heightened risk of prediabetes and type 2 diabetes development. This transmission creates a vicious cycle increasing the presence of diabetes from one generation to another, leading to the...

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PMID: 39556447
DOI: 10.2337/dbi24-0014

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