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Evaluating Antimalarial Proteasome Inhibitors for Efficacy in Babesia Blood Stage Cultures

28 Oct 2024

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Tick-transmitted Babesia are a major global veterinary threat and an emerging risk to humans. Unlike their Plasmodium relatives, these erythrocyte-infecting Apicomplexa have been largely overlooked and lack specific treatment. Selective targeting of the Babesia proteasome holds promise for drug development. In this study, we screened a library of peptide...

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PMID: 39554424
DOI: 10.1021/acsomega.4c04564

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