Developmental trajectories of atopic dermatitis with multiomics approaches in the infant gut: COCOA birth cohort.

doi:10.1016/j.jaci.2024.10.036

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Article

Developmental trajectories of atopic dermatitis with multiomics approaches in the infant gut: COCOA birth cohort.

The Journal of allergy and clinical immunology - 1 Feb 2025

Lee Eun, Kim Jeong-Hyun, Lee So-Yeon, Lee Si Hyeon, Park Yoon Mee, Oh Hea Young, Yeom Jeonghun, Ahn Hee-Sung, Yoo Hyun Ju, Kim Bong-Soo, Yun Sun Mi, Choi Eom Ji, Song Kun Baek, Park Min Jee, Ahn Kangmo, Kim Kyung Won, Shin Youn Ho, Suh Dong In, Song Joo Young, Hong Soo-Jong

Abstract excerpt

BACKGROUND: An understanding of the phenotypes and endotypes of atopic dermatitis (AD) is essential for developing precision therapies. Recent studies have demonstrated evidence for the gut-skin axis in AD. OBJECTIVE: We sought to determine the natural course and clinical characteristics of AD phenotypes and investigate their mechanisms on the basis of multiomics analyses. METHODS: Latent class trajectory...

Read the complete abstract on PubMed

Topics

Humans
Dermatitis, Atopic
Infant
Female
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Gastrointestinal Microbiome

Phenotype

Child

Child, Preschool

Birth Cohort

Cohort Studies

Transcriptome

Multiomics

Source

Open in PubMed

Identifiers

PMID: 39547281
DOI: 10.1016/j.jaci.2024.10.036

Genes

ACSS2

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