Article
Microbial genetic variation impacts host eco-immunological strategies and microparasite fitness in Lyme borreliae-reptile system.
Ticks and tick-borne diseases - 1 Nov 2024
Nowak Tristan A, Fernandes Carly, Malfetano Jill, Lasek-Nesselquist Erica, Combs Matthew, Strle Klemen, Burke Russell L, Lin Yi-Pin
Abstract excerpt
Tolerance and resistance are two host eco-immunological strategies in response to microparasite invasion. In the strategy of "resistance", host responses are induced to decrease microparasite replication while the "tolerance" strategy allows hosts coexistence with microparasites by minimizing responses to avoid immune-mediated damage. The causative agent of Lyme disease is a group of genotypically diverse...
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