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Article

Analysis of behavioral flow resolves latent phenotypes.

Nature methods - 1 Dec 2024

von Ziegler Lukas M, Roessler Fabienne K, Sturman Oliver, Waag Rebecca, Privitera Mattia, Duss Sian N, O'Connor Eoin C, Bohacek Johannes

Abstract excerpt

The accurate detection and quantification of rodent behavior forms a cornerstone of basic biomedical research. Current data-driven approaches, which segment free exploratory behavior into clusters, suffer from low statistical power due to multiple testing, exhibit poor transferability across experiments and fail to exploit the rich behavioral profiles of individual animals. Here we introduce a pipeline to capture...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39533008
DOI: 10.1038/s41592-024-02500-6
PMCID: PMC11621029

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