Article
Generation of human induced pluripotent stem cell lines derived from patients of cystic biliary atresia.
Human cell - 13 Nov 2024
Ge Ningxin, Suzuki Kan, Sato Iori, Noguchi Michiya, Nakamura Yukio, Matsuo-Takasaki Mami, Fujishiro Jun, Hayashi Yohei
Abstract excerpt
Biliary atresia (BA), resulting from abnormal development of the liver's internal or external bile ducts, can lead to liver damage and potentially fatal cirrhosis. Type I cystic biliary atresia is a relatively uncommon, but clinically significant variant of BA. It is critical to develop experimental models of BA to examine the etiology and pathogenesis, which remain elusive, and to develop future therapeutics....
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