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Real-Time Assessment of H. pylori Infection to Guide Molecular Antibiotic Resistance Testing: A Combined Endoscopy-Gastric Juice Analysis Approach.

Alimentary pharmacology & therapeutics - 1 Feb 2025

Vasapolli Riccardo, Ailloud Florent, Spießberger Beate, Malfertheiner Peter, Suerbaum Sebastian, Schulz Christian

Abstract excerpt

BACKGROUND: Helicobacter pylori antibiotic resistance is the most relevant cause of treatment failure. Antibiotic susceptibility testing (AST) allows for selecting the appropriate eradication regimen. AIMS: To assess the diagnostic accuracy of gastric aspirate-based genotypic AST (G-AST) for detecting clarithromycin and levofloxacin resistance compared with conventional phenotypic AST (P-AST). METHODS: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39530235
DOI: 10.1111/apt.18378

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