Article
Architectural crypt distortions in ulcerative colitis: Time for reappraisal.
Journal of gastroenterology and hepatology - 1 Dec 2024
Rubio Carlos A, Lang-Schwarz Corinna, Vieth Michael
Abstract excerpt
Chronic mucosal inflammation and architectural crypt distortions (ACD) are essential for the histologic diagnosis of ulcerative colitis (UC). ACD in UC has been defined as irregularly arranged, dilated, branched, and shortened crypts with inequality of inter-crypt distance. However, neither the diagnostic sections' crypt phenotype nor the cutting mode have been considered. In this regard, previous studies showed...
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