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Article

Phenotypic Biomarkers of Aqueous Extracellular Vesicles from Retinoblastoma Eyes.

International journal of molecular sciences - 30 Oct 2024

Amacker Anne, Peng Chen-Ching, Jiang Nan, Sirivolu Shreya, Higa Nikki, Stachelek Kevin, Reiser Bibiana, Kuhn Peter, Cobrinik David, Neviani Paolo, Berry Jesse L, Jovanovic-Talisman Tijana, Xu Liya

Abstract excerpt

Recent advancements in aqueous humor (AH) cell-free DNA (cfDNA) genomics have opened new avenues for ex vivo molecular profiling of retinoblastoma (RB), the most common pediatric intraocular malignancy, where biopsy is typically prohibited. While these insights offer a genetic blueprint of the tumor, they lack multi-omic molecular phenotyping, which is essential for understanding the functional state....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 39519212
DOI: 10.3390/ijms252111660
PMCID: PMC11545953

Genes

CD63
CD81
CD9

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