Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The influence of a human macronutrient-matched diet on phenotypes in old mice.

GeroScience - 1 Apr 2025

Darrah Mary A, Longtine Abigail G, Greenberg Nathan T, Mahoney Sophia A, Venkatasubramanian Ravinandan, VanDongen Nicholas S, Reisz Julie A, D'Alessandro Angelo, Seals Douglas R, de Quiros Miranda Yara Bernaldo, Clayton Zachary S

Abstract excerpt

Preclinical rodent models are essential research tools for improving understanding of physiological aging processes in humans. However, the translatability of findings obtained leveraging rodent models to humans is limited, likely due in part to differences in macronutrient composition of the diets. Here, we investigated the impact of a 3-month diet intervention in old male C57BL/6JN mice in which the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice
Share to Aging

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Frailty

Share to Mice, Inbred C57BL

Share to Nutrients

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 39514173
DOI: 10.1007/s11357-024-01423-6
PMCID: PMC11978591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The influence of a human macronutrient-matched diet on phenotypes in old mice.PMID 39514173Read ↗

Improving Metabolic Health Through Precision Dietetics in Mice.Semantic proximity Read ↗

The new total Western diet for rodents does not induce an overweight phenotype or alter parameters of metabolic syndrome in mice.Semantic proximity Read ↗

Drugs, Nutrients, and Phytoactive Principles Improving the Health Span of Rodent Models of Human Age-Related DiseasesSemantic proximity Read ↗

A Ketogenic Diet Extends Longevity and Healthspan in Adult MiceSemantic proximity Read ↗

A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice.Semantic proximity Read ↗

Regulators of health and lifespan extension in genetically diverse mice on dietary restrictionSemantic proximity Read ↗

Dietary regulation in health and diseaseSemantic proximity Read ↗

Regulators of health and lifespan extension in genetically diverse mice on dietary restrictionSemantic proximity Read ↗

Quantification of healthspan in aging mice: Introducing FAMY and GRAILSemantic proximity Read ↗

Phenotypic Frailty Assessment in Mice: Development, Discoveries, and Experimental Considerations.Semantic proximity Read ↗

Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in miceSemantic proximity Read ↗

Body Weight Loss, Tissue Wasting and Shortened Lifespan in Late Middle-aged Mice on Imbalanced Essential/Non-essential Amino Acids DietSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.