Article
Associations of physiologic subtypes based on HOMA2 indices of β-cell function and insulin sensitivity with the risk of kidney function decline, cardiovascular disease, and all-cause mortality from the 4C study.
Cardiovascular diabetology - 7 Nov 2024
Luo Peiqiong, Li Danpei, Guo Yaming, Meng Xiaoyu, Kan Ranran, Pan Limeng, Xiang Yuxi, Mao Beibei, He Yi, Wang Siyi, Yang Yan, Liu Zhelong, Xie Junhui, Zhang Benping, He Wentao, Hu Shuhong, Zhou Xinrong, Yu Xuefeng
Abstract excerpt
BACKGROUND: Previous studies have been limited by their inability to differentiate between the effects of insulin sensitivity and β-cell function on the risk of kidney function decline, cardiovascular disease (CVD), and all-cause mortality. To address this knowledge gap, we aimed to investigate whether the physiological subtypes based on homeostasis model assessment-2 (HOMA2) indices of β-cell function (HOMA2-B)...
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