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myh9b is a critical non-muscle myosin II encoding gene that interacts with myh9a and myh10 during zebrafish development in both compensatory and redundant pathways.

G3 (Bethesda, Md.) - 8 Jan 2025

Rolfs Laura A, Falat Elizabeth J, Gutzman Jennifer H

Abstract excerpt

Non-muscle myosin (NMII) motor proteins have diverse developmental functions due to their roles in cell shape changes, cell migration, and cell adhesion. Zebrafish are an ideal vertebrate model system to study the NMII encoding myh genes and proteins due to high sequence homology, established gene editing tools, and rapid ex utero development. In humans, mutations in the NMII encoding MYH genes can lead to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39503257
DOI: 10.1093/g3journal/jkae260
PMCID: PMC11708221

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